Visual Phasing Six Siblings with the Fox Spreadsheet: Part 13: Chromosome 12

Here is Chromosome 12 from the Fox Spreadsheet:

I have made a guess at placing crossovers and assigning them to my siblings and me. In fact, in places, I am quite sure these crossovers are not right.

Cousin Matches Ferret Out Crossovers

Here are some matches with Hartley cousin Joyce:

These matches represent a paternal crossovers for Jon at 106.7 and Heidi at 75M.

I expect that Joel, Sharon and Lori will also have Frazer DNA in this area. I also note that I have not given Jim any crossovers. If this holds true, he will have full chromosomes of one grandparent on the maternal and paternal sides.

Here’s some more Hartley DNA from my father’s first cousin Maury:

When I compare Maury’s match to me compared to the crossover positions I have, I see that I have the D and F crossover lines backwards:

I gave myself (Joel) a big dose of Frazer after the Hartley crossover.

Matches with Frazer cousin Gladys give crossovers to Lori and Heidi:

Maternal Cousins – A Problem Have I

Unfortunately, I have imported 8 maternal cousins into the Fox Spreadsheet and none of them match me or my 5 siblings on Chromoosme 12. What to do? I can go further down the list.

Rathfelder Cousin Otis

Otis matches on my Rathfelder side. Here is his match with me and my siblings on Chromosome 12:

So not only does he match, but he points out two crossovers: Joel at 46.4 and Lori and 45.4M. Thanks to Otis, I get this:

Frazer Cousin Paul and Lori


Here we see a few things. I forgot to add Sharon’s Frazer DNA. The other thing is that Frazer DNA goes by Jon and Lori’s crossovers. That means that their crossovers need to be on their maternal sides.

Checking the All-Important Segment Map

The Segment Map compared to the Gedmatch sibling pairings keep me on track:

Filling in the Left Side of Chromosome 12

If the crossovers are correct on the left side of Chromosome 12, I’ll be able to fill that side in with no problem.

I don’t show Sharon or Jim with crossovers. I moved Sharon’s DNA to the left. However, I see a problem already as Sharon and Lori are FIR in the first section. That means that if Sharon’s first segment is right, Lori should also have Frazer and Rathfelder DNA. However, Lori shows a crossover which would indicate a change going left from her already Frazer/Rathfelder DNA.

I’m not reallys sure of the DLFD area, so I’ll take a detailed look.

Detailed Look at the DLFD Crossover Area of Chromosome 12

The V & S comparison shows a change at 16.8M, but I don’t show a crossover for V or S:

Before I looked at this in a more detailed way, I have a few observations:

I don’t see changes for L. I do see that V has two changes at 16.8M. This may be the difference. Another thing I see is that there doesn’t appear to be a need for the first D crossover. I’ll take that out.

I’m trying to avoid the detailed analysis, so I’ll see how this works out:

Here is the all-important comparison:

A Problem with Crossovers at 111M

I had a problem figuring out things around S, L, and H on the right-hand side of Chromosome 12:

The changes don’t align well. Also there is a change between V & D at 111.6M, but no crossover for V or D. That means that I should start at 111M and go up to 118 in my analysis:

By just looking at the Jim (V) comparisons, it appears that the S crossover should be a V and that the H and L may be right. But I need to continue on. The final sibling comparison that I do is here between Heidi and Lori:

This shows an NIR going to an FIR. That means that there must be a small HIR between the NIR and FIR. Here is the close-up version at Gedmatch:

This shows two changes between about 117.3 and 117.7.

After I look up all the comparisons, I sort by position number:

Unfortunately, the results are not as definitive as I would have liked. The F at the top was not in question. The last L and H seem clear. The other crossovers are probably V and S.  L and H are not needed in the first unboxed areas, as they are already combined with either V’s or S’s.

Here is my interpretation of the above analysis:

Here, I erased Jim’s Lentz DNA on the right as I have him with a crossover now. I’ll try solving the Chromosome with my new crossover arrangement:

The comparison looks about right:

However, if I look too long, I get eye fatigue.

Summary and Conclusions

  • The problem areas for the crossovers were where I thought that they would be.
  • I was able to solve one problem area without doing a full detailed analysis.
  • Solving these Chromosomes mostly comes down to solving the problem areas. These are where the crossovers are close and difficult to determine.
  • Jim, who was the last sibling to have his DNA tested, had all Hartley DNA on his paternal side. This is important as the other siblings were missing Hartley DNA in a large section of the Chromosome.
  • This Chromosome has full coverage for all four grandparents.

 

 

 

 

 

 

 

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