{"id":7955,"date":"2018-11-19T20:58:40","date_gmt":"2018-11-19T20:58:40","guid":{"rendered":"http:\/\/www.jmhartley.com\/HBlog\/?p=7955"},"modified":"2018-11-19T20:58:40","modified_gmt":"2018-11-19T20:58:40","slug":"visual-phasing-six-siblings-with-the-fox-spreadsheet-part-12-chromosome-11","status":"publish","type":"post","link":"http:\/\/www.jmhartley.com\/HBlog\/2018\/11\/19\/visual-phasing-six-siblings-with-the-fox-spreadsheet-part-12-chromosome-11\/","title":{"rendered":"Visual Phasing Six Siblings with the Fox Spreadsheet: Part 12: Chromosome 11"},"content":{"rendered":"

In my previous Blog<\/a>, I was hoping for and easier Chromosome to visually phase. I don’t think that Chromosome 10 was more difficult than Chromosome 9, but a mistake I made gave me some problems.<\/p>\n

Chromosome 11<\/h2>\n

Here is a first shot at drawing DNA lines.<\/p>\n

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The first line is for me (Joel – D). This will be where I have a change in DNA. The next three lines were confusing, so I’ll wait to figure those out. I put my original findings into a spreadsheet:<\/p>\n

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I need the spreadsheet to keep track of the locations of the changes. The yellow parts and the question marks are areas that need work or further analysis. Some of these area may be more clear once I look at our cousin matches.<\/p>\n

Cousin Matches<\/h2>\n

Cousin Maury on my Hartley side gives two crossovers, in an area where I was confused:<\/p>\n

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This shows that Jim (V) has a crossover at 16.9M and Heidi has one at 17.5M. This saves me some time. I’ll give the third question mark to Jim (V). Jim has changes in his five sibling comparisons. These can be seen in the first five comparisons below:<\/p>\n

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Next, I find a crossover I missed for Joel (D) thanks to matches with Hartley cousin Joyce:<\/p>\n

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This crossover is at 77.4. This describes another confusing area that I had noted on my spreadsheet:<\/p>\n

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I’ll replace the ? with a D at 77.4.<\/p>\n

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Hartley cousin James has some huge matches with me and my siblings on Chromosome 11:<\/p>\n

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I could have inferred more Frazer DNA from the Hartley matches, but I haven’t added them in yet. For example, Jim will have a lot of Frazer DNA as he doesn’t match James on the Hartley side. I have already filled in all of Heidi’s paternal Chromosome 11 with these three Hartley matches.<\/p>\n

Inese adds in some Rathfelder DNA:<\/p>\n

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Here I made a few assumptions. I assumed that I had the right crossovers. I assumed where the paternal side DNA went through a crossover, that the crossover belonged to the maternal side. In doing this, I completed Lori’s Chromosome 11. However, I have not checked the work.<\/p>\n

Next I’ll look at Lentz cousin Judith:<\/p>\n

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While looking at this match, it appeared that I had a crossover for Jon in this area that didn’t belong, so I took it out. I have the H crossover at 122.3. That means that Judith’s matches start before the H crossover which is at about 122.8<\/p>\n

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However, I added Lentz DNA in for Heidi at that location. She needs Lentz DNA there due to her crossover. My assumption is that due to her crossover, her match with Judith went below the reportable level of 7cM. This should be easy to check:<\/p>\n

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This is Judith’s matching with Sharon, Jon, Jim, Heidi (#4), Lori and Joel. The pink match with Lori appears to be a false match.<\/p>\n

Checking the Segment Map for Peace of Mind<\/h3>\n

I’ve gone a way without checking the Segment Map. Here is the comparison between the Segment Map and the Gedmatch sibling comparisons:<\/p>\n

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This is a bit of an eye workout. I put purple around what appears to be the problem areas. This area starts with a Heidi crossover. The three problem areas have Lori in common. The positions are around 120 to 122M.<\/p>\n

Detailed Analysis<\/h2>\n

Before I do a detailed analysis, I’ll do a semi-detailed analysis:<\/p>\n

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These are the sibling pairs where I am seeing the changes. It seems like there are a lot of H’s and L’s. It could be that I will need to add another L crossover. That would also be consistent with the mistakes that I outlined in purple above. Without even finishing my detailed analysis, I can see what is going on:<\/p>\n

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V, F and D are each matching with H once and L twice. That means that H has one crossover and L has two. I finished the analysis and sorted by position:<\/p>\n

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I had taken out an F crossover above that should have been an L crossover. Here is the production update:<\/p>\n

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Here is the revised Segment Map\/Gedmatch comparison:<\/p>\n

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This shows that I am back on track.<\/p>\n

Next, I’ll try to solve the Chromosome:<\/p>\n

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This needs to be checked:<\/p>\n

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This looks OK.<\/p>\n

Summary and Conclusions<\/h2>\n